A Trial of Bardoxolone Methyl in Patients with ADPKD (FALCON)

Multiple Locations

Overview

 

FALCON is a Phase 3 clinical study evaluating the effectiveness and safety of bardoxolone methyl (an oral investigational drug) in patients with Autosomal Dominant PKD.

Before participating in FALCON, patients must complete two screening visits at one of the study centers. Eligible patients will be randomly assigned (like the flip of a coin) to receive either bardoxolone methyl or placebo (an inactive capsule). The group of patients assigned to bardoxolone methyl will be compared to the group of patients assigned to placebo in order to help researchers better understand the effects on PKD.

The investigational drug, study-related procedures and doctor visits will be provided at no cost. If you travel to the site for your study visits, travel expenses will be reimbursed and compensation for study-related time may be compensated.

 

You may be eligible for this study if you:
● Are between 18 to 70 years of age
● Have been diagnosed with ADPKD
● Have a lab value eGFR between 30 to 90 mL/min/1.73 m2 (18 to 55 years old) or between 30 to 44 mL/min/1.73 m2 (56 to 70 years old)

 

Exclusion Criteria:
● Current use of tolvaptan
● History of intracranial aneurysms;
● Kidney or any other solid organ transplant recipient or a planned transplant during the study;
● Systemic immunosuppression for more than 2 weeks or anticipated need for immunosuppression during the study;
● Women who are pregnant or breastfeeding;

 

If you’re interested in participating, contact:
+1 469-442-4754
FALCON@reatapharma.com

Locations:

 

Alabama

University of Alabama at Birmingham

Birmingham, Alabama 35294

Principal Investigator: Dana Rizk, MD

 

Nephrology Consultants, LLC

Huntsville, Alabama 35805

Principal Investigator: Michael Quadrini, MD

 

Arizona

AKDHC

Glendale, Arizona 85306

Principal Investigator: Peter Santos, MD

 

Aventiv Research, Inc

Mesa, Arizona 85210

Principal Investigator: Mandeep Sahani, MD

 

University of Arizona

Tucson, Arizona 85719

Principal Investigator: Frank Brosius, MD

 

California

California Institute Renal Research

La Mesa, California 91942

Principal Investigator: George Fadda, MD

 

University of California, Los Angeles

Los Angeles, California 90025

Principal Investigator: Anjay Rastogi, MD

 

Amicis Research Center

Northridge, California, 91324

Principal Investigator: Dabel Pascal, MD

 

Apex Research of Riverside

Riverside, California 92505

Principal Investigator: Joseph Lee, MD

 

University of California, San Francisco

San Francisco, California, 94143

Principal Investigator: Meyeon Park, MD

 

Keck/USC

Los Angeles, California, 90033

Principal Investigator: Nuria Pastor-Soler, MD

 

Colorado

Western Nephrology

Arvada, Colorado 80002

Principal Investigator: Harmeet Singh, MD

 

Connecticut

Yale University School of Medicine

New Haven, Connecticut 06520

Principal Investigator: Neera Dahl, MD

 

Florida

Volunteer Medical Research

Port Charlotte, Florida 33952

Principal Investigator: Kianoosh Kaveh, MD

 

Florida Premier Research Institute, LLC

Winter Park, Florida 32789

Principal Investigator: Jorge Kusnir, MD

 

Georgia

Emory University

Atlanta, Georgia 30322

Principal Investigator: Frederic Rahbari-Oskoui, MD

 

Idaho

Boise Kidney & Hypertension, PLLC

Caldwell, Idaho 83605

Principal Investigator: Arnold Silva, MD

 

Boise Kidney & Hypertension, PLLC

Meridian, Idaho 83642

Principal Investigator: Arnold Silva, MD

 

Illinois

Northwestern University

Chicago, Illinois 60611

Principal Investigator: Jennifer Tuazon, MD

 

University of Chicago

Chicago, Illinois 60617

Principal Investigator: Arlene Chapman, MD

 

NorthShore University Health System

Evanston, Illinois 60201

Principal Investigator: Stuart Sprague, MD

 

Kansas

University of Kansas Medical Center

Kansas City, Kansas 66224

Principal Investigator: Kerri McGreal, MD

 

Kansas Nephrology Research Institute, LLC

Wichita, Kansas 67214

Principal Investigator: Dennis Ross, MD

 

Louisiana

Renal Associates of Baton Rouge

Baton Rouge, Louisiana 70808

Principal Investigator: Michael Roppolo, MD

 

Northwest Louisiana Nephrology

Shreveport, Louisiana 71101

Principal Investigator: Marwan Kaskas, MD

 

Maryland

University of Maryland School of Medicine

Baltimore, Maryland 21201

Principal Investigator: Stephen Seliger, MD

 

Massachusetts

Tufts Medical Center

Boston, Massachusetts 02111

Principal Investigator: Ronald Perrone, MD

 

Beth Israel Deaconess Medical Center

Boston, Massachusetts 02215

Principal Investigator: Theodore Steinman, MD

 

Michigan

Paragon Health PC d/b/a Nephrology Center PC

Kalamazoo, Michigan 49007

Principal Investigator: Than Oo, MD

 

Michigan Kidney Consultants

Pontiac, Michigan 48341

Principal Investigator: Fahd Al-Saghir, MD

 

Minnesota

Mayo Clinic

Rochester, Minnesota 55905

Principal Investigator: Vicente Torres, MD

 

Missouri

Clinical Research Consultants, LLC

Kansas City, Missouri 64111

Principal Investigator: Ahmed Awad, MD

 

Washington University in St. Louis

Saint Louis, Missouri 63110

Principal Investigator: George Jarad, MD

 

New York

Nephrology Associates, P.C.

Flushing, New York 11355

Principal Investigator: Bruce Spinowitz, MD

 

North Carolina

Mountain Kidney & Hypertension Associates

Asheville, North Carolina 28801

Principal Investigator: Joseph Aiello, MD

 

Metrolina Nephrology Associates

Charlotte, North Carolina 28204

Principal Investigator: Peale Chuang, MD

 

North Carolina Nephrology

Raleigh, North Carolina 27609

Principal Investigator: Jason Eckel, MD

 

Ohio

University of Cincinnati College of Medicine

Cincinnati, Ohio 45267

Principal Investigator: Kotagal Kant, MD

 

Cleveland Clinic

Cleveland, Ohio 44195

Principal Investigator: Richard Fatica, MD

 

Remington-Davis Clinical Research

Columbus, Ohio 43215

Principal Investigator: Kevin Schroeder, MD

 

Pennsylvania

Northeast Clinical Research Center

Bethlehem, Pennsylvania 18017

Principal Investigator: Nelson Kopyt, MD

 

University of Pennsylvania

Philadelphia, Pennsylvania 19014

Principal Investigator: Simin Goral, MD

 

Children’s Hospital of Philadelphia

Philadelphia, Pennsylvania 19104

Principal Investigator: Kevin Meyers, MD

 

South Carolina

Columbia Nephrology Associates, PA

Columbia, South Carolina 29203

Principal Investigator: Asha Bailey, MD

 

Tennessee

Nephrology Associates, P.C.

Nashville, Tennessee 37205

Principal Investigator: Douglas Linfert, MD

 

Texas

Research Management, Inc.

Austin, Texas 78751

Principal Investigator: Judith Betts, MD

 

Research Management, Inc.

Austin, Texas 78758

Principal Investigator: Eileen Cook, MD

 

Renal Disease Research Institute

Dallas, Texas 75235

Principal Investigator: Ankit Mehta, MD

 

DaVita Med Center

Houston, Texas 77004

Principal Investigator: Stephen Fadem, MD

 

Clinical Advancement Center

San Antonio, Texas 78215

Principal Investigator: Pablo Pergola, MD

 

Vermont

University of Vermont Medical Center

Burlington, Vermont 05401

Principal Investigator: Richard Solomon, MD

 

Virginia

University of Virginia

Charlottesville, Virginia 22908

Principal Investigator: Sana Khan, MD

 

Wisconsin

Medical College of Wisconsin

Milwaukee, Wisconsin 53226

Principal Investigator: Ashraf El-Meanawy, MD

 

Australia: New South Wales, Queensland, South Australia, Victoria and Western Australia

United Kingdom: Cambridge and London